中国人民大学
lvleiyang2008@163.com
个人情况：
男，1989.6生，山东省，中共党员
Email：lvleiyang2008@163.com
学习、工作经历：
2020/9—至今 副教授 中国人民大学 化学系
2019/9—2020/8 博士后 McGill University 导师 李朝军 教授
2017/9—2019/8 博士后 兰州大学/McGill University 导师 李朝军 教授
2012/9—2017/7 博士 中国人民大学 导师 李志平 教授
2008/9—2012/7 学士 青岛科技大学
研究方向：
绿色合成化学
有机氟化学
仿生药物合成
合成生物学
获得奖项及荣誉：
中国人民大学“杰出学者”（青年B岗）
博士生国家奖学金 (2014年, 2015年)
光华奖学金 (2016年)
中国人民大学第十届“学术新星”奖 (2016年)
第十四届全国均相催化“优秀学生报告奖”(2015年)
代表性论文：
[1] Qian, H.; Cheng, Z. P.; Luo, Y.; Lv, L.*; Chen, S.*; Li, Z.* Pd/IPrBIDEA-Catalyzed Hydrodefluorination of gem-Difluorocyclopropanes: Regioselective Synthesis of Terminal Fluoroalkenes. J. Am. Chem. Soc. 2023. DOI: 10.1021/jacs.3c07992.
[2] Qian, H.; Nguyen, H. D.; Lv, L.*; Chen, S.*; Li, Z.* Chemo-, Stereo- and Regioselective Fluoroallylation/Annulation of Hydrazones with gem-Difluorocyclopropanes via Tunable Palladium/NHC Catalysis. Angew. Chem. Int. Ed. 2023, e202303271.
[3] Lou, C.; Feng, Y.; Huang, Q.; Lv, L.*; Li, Z.* Visible Light-Induced Decarboxylative Peroxidation of Carboxylic Acids: Metal-Free Synthesis of Benzyl Peroxides. Asian J. Org. Chem. 2023, DOI: 10.1002/ajoc.202300408.
[4] Yan, Y.; Qian, H.; Lv, L.*; Li, Z.*. Pd/NHC-Catalyzed Ring-Opening of gem-Difluorocyclopropanes with Malonates Via Selective C-C Bond Cleavage: Synthesis of Monofluoroalkenes. J. Org. Chem. 2023, DOI: 10.1021/acs.joc.3c00744.
[5] Mao, K.; Lv, L.*; Li, Z.* Amine-Induced Selective C–C Bond Cleavage of 2,2,2-Trifluoroethyl Carbonyls for the Synthesis of Ureas and Amides. J. Org. Chem. 2023, 88, 10137–10146.
[6] Lv, L.*; Qian, H. Developments and Applications of Allyl-(aza)allyl Coupling Reactions. Green Synth. Catal. 2023, 4, 190-205.
[7] Luo, Y.; Lv, L.*; Li, Z.* Light-promoted Germylation of Aryl Propiolamides/Alkynoates: Synthesis of Ge-Containing Spiro[4.5]trienones and Vinylgermanes. ChemCatChem 2023, 15, e202300467.
[8] Shu, S.; Wang, L.; Lv, L.*; Li Zhiping *.Copper-Catalyzed [3+2] Annulation of Pyridinium Ylides with α-CF3 Ketones: Synthesis of Functionalized 2-Fluoroindolizines. Asian J. Org. Chem. 2023, 12, e202300075.
[9] Lv, L.*; Qian, H.; Crowell, A. B.; Chen, S.*; Li, Z.* Pd/NHC-Controlled Regiodivergent Defluorinative Allylation of gem-Difluorocyclopropanes with Allylboronates. ACS. Catal. 2022, 12, 6495-6505.
[10] Lv, L.*; Qian, H.; Li, Z.* Catalytic Diversification of gem-Difluorocyclopropanes: Recent Advances and Challenges. ChemCatChem 2022, 14, e202200890.
[11] Liu, F.; Lv, L.*; Ma, Y.*; Li, Z.* Copper-Catalyzed Radical Difluoromethylation-Peroxidation of Alkenes: Synthesis of β-Difluoromethyl. Peroxides. Asian J. Org. Chem. 2022, 11, e202200393.
[12] Wang, L.; Shu, S.; Lv, L.*; Li, Z.* Copper-Catalyzed Remote Trifluoromethylthiolation-Peroxidation of Unactivated Alkenes via 1,5-Hydrogen Atom Transfer. Tetrahedron Lett. 2022, 104, 154029.
[13] Gao, G.; Mao, K.; Lv, L.*; Li, Z.* Three-Component Coupling of α-Trifluoromethyl Carbonyls, Azides and Amines for the Regioselective Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles. Adv. Synth. Catal. 2022, 364, 1402-1408.
[14] Luo, Y.; Xu, B.; Lv, L.*; Li, Z.* Copper-Catalyzed Three-Component Germyl Peroxidation of Alkenes. Org. Lett. 2022, 24, 2425-2430.
[15] Luo, Y.; Lv, L.*; Li, Z.* Copper-Catalyzed Germyl-Azidation of Alkenes with Germanium Hydrides and Trimethylsilyl Azide. Org. Lett. 2022, 24, 8052-8056.
[16] Ma, Y.; Lv, L.*; Li, Z.* β-Perfluoroalkyl Peroxides as Fluorinated C3-Building Blocks for the Construction of Benzo[4,5]imidazo[1,2-a]pyridines. J. Org. Chem. 2022, 87, 1564-1573.
[17] Wang, L.; Lv, L.*; Li, Z.* Concomitant Functionalization of Two Different Ketones by Merging Brønsted Acid Catalysis and Radical Relay Coupling. Org. Chem. Front. 2022, 9, 1561-1566.
[18] Lv, L.*; Qian, H.; Ma, Y.; Huang, S.; Yan, X.; Li, Z.* Ligand-Controlled Regioselective and Chemodivergent Defluorinative Functionalization of gem-Difluorocyclopropanes with Simple Ketones. Chem. Sci. 2021, 12, 15511-15518. (Hot paper)
[19] Lv, L.; Gao, G.; Luo, Y.; Mao, K.; Li, Z.* Three-Component Reactions of Alpha-CF3 Carbonyls, NaN3, and Amines for the Synthesis of NH-1,2,3-Triazoles. J. Org. Chem. 2021, 86, 17197-17212.
[20] Lou, C.; Wang, X.; Lv, L.*; Li, Z.* Iron-Catalyzed Ring-Opening Reactions of Cyclopropanols with Alkenes and TBHP: Synthesis of 5-Oxo Peroxides. Org. Lett. 2021, 23, 7608-7612.
[21] Luo, Y.; Tian, T.; Nishihara, Y.; Lv, L.*; Li, Z.* Iron-Catalysed Radical Cyclization to Synthesize Germanium-Substituted Indolo[2,1-a]isoquinolin-6(5H)-ones and Indolin-2-ones. Chem. Commun. 2021, 57, 9276-9279.
[22] Wang, X.; Lou, C.; Lv, L.*; Li, Z.* Annulative pi-Extension (APEX) of Indoles to Pyrido[1,2-a]indoles Using 4-Oxo Peroxides as C4 Units. Org. Lett. 2021, 23, 5978-5982.
[23] Ma, Y.; Chen, Y.; Lv, L.*; Li, Z.* Regioselective Synthesis of Emission Color‐Tunable Pyrazolo[1,5‐a]pyrimidines with β,β‐Difluoro Peroxides as 1,3‐Bis‐Electrophiles. Adv. Synth. Catal. 2021, 363, 3233-3239.
[24] Wang, L.; Ma, Y.; Jiang, Y.; Lv, L.*; Li, Z.* A Mn-Ratalyzed Remote C(sp(3))-H bond Peroxidation Triggered by Radical Trifluoromethylation of Unactivated Alkenes. Chem. Commun. 2021, 57, 7846-7849.
[25] Lv, L.*; Li, C.-J.* Pd-Catalyzed Defluorinative Alkylation of gem-Difluorocyclopropanes: Switching Regioselectivity via Simple Hydrazones. Angew. Chem. Int. Ed. 2021, 60, 13098-13104.
[26] Li, L.; Huang, S.; Mao, K.; Lv, L.*; Li, Z.* Synthesis of Isoxazoles via Cyclization of β-Fluoro Enones with Sodium Azide. Tetrahedron. Lett. 2021, 71, 153052.
[27] Lv, L.*; Li, C.-J.* Ruthenium Catalyzed β-Selective Alkylation of Vinylpyridines with Aldehydes/Ketones via N2H4 Mediated Deoxygenative Couplings. Chem. Sci. 2021, 12, 2870-2875.
[28] Tian, T.; Wang, X.; Lv, L.*; Li, Z.* Iron-Catalyzed Acylation-Functionalization of Unactivated Alkenes with Aldehydes. Chem. Commun. 2020, 56, 14637-14640.
[29] Yu, L. ‡; Lv, L. ‡; Qiu, Z.; Chen, Z.; Tan, Z.; Liang, Y.-F.; Li, C.-J. Pd-Catalyzed Formal Hydroalkylation of Aryl-Substituted Alkynes with Hydrazones. Angew. Chem. Int. Ed. 2020, 59, 14009-14013. (contributed equally) (Hot paper)
[30] Lv, L. ‡; Yu, L. ‡; Qiu, Z.; Li, C.-J. Switch in Selectivity for the Formal Hydroalkylation of 1,3-Dienes and Enynes with Simple Hydrazones. Angew. Chem. Int. Ed. 2020, 59, 6466-6472. (VIP paper)
[31] Lv, L. ‡; Zhu, D. ‡; Li, C.-J. Direct Dehydrogenative Alkyl Heck-Couplings of Vinylarenes with Umpolung Aldehydes Catalyzed by Nickel. Nat. Commun. 2019, 10, 715.
[32] Lv, L. ‡; Qiu, Z. ‡; Li, J.; Liu, M.; Li, C.-J. N2H4 as Traceless Mediator for Homo- and Cross- Aryl Coupling. Nat. Commun. 2018, 9, 4739.
[33] Lv, L. ‡; Zhu, D. ‡; Tang, J.; Qiu, Z.; Li, C.-C.; Gao, J.; Li, C.-J. Cross-Coupling of Phenol Derivatives with Umpolung Aldehydes Catalyzed by Nickel. ACS Catal. 2018, 8, 4622-4627.
[34] Lv, L.; Zhu, D.; Qiu, Z.; Li, J.; Li, C.-J. Nickel-Catalyzed Regioselective Hydrobenzylation of 1,3-Dienes with Hydrazones. ACS Catal. 2019, 9, 9199-9205.
[35] Zhu, D.‡; Lv, L.‡; Li, C.-C.; Ung, S.; Gao, J.; Li, C.-J. Umpolung of Carbonyls as Alkyl Organometallic Reagent Surrogates for Palladium Catalyzed Allylic Alkylation. Angew. Chem. Int. Ed. 2018, 57, 16520-16524. (contributed equally)
[36] Zhou, Z.-Z.‡; Liu, M.‡; Lv, L.‡; Li, C.-J. Silver (I)-Catalyzed Widely Applicable Aerobic 1,2-Diol Oxidative Cleavage. Angew. Chem. Int. Ed. 2018, 57, 2616-2620. (contributed equally)
[37] Lv, L.*; Li, Z. * FeCl3-Catalyzed Regio-Divergent Carbosulfenylation of Unactivated Alkenes: Construction of Medium-Sized Ring. J. Org. Chem. 2018, 83, 10985-10994.
[38] Lv, L.; Li, Z. Iron-Catalyzed Oxidative Cyclization of 1,6-Enones with Aldehydes: Synthesis of Functionalized 3,4-Dihydro-2H-pyrans. Chin. J. Chem. 2017, 35, 303-306.
[39] Lv, L.; Li, Z. Cycloalkylation of C(sp3)-H Bond with Neighboring Carboxylic Acid as Traceless Activating Group. J. Org. Chem. 2017, 82, 2689-2702.
[40] Lv, L.; Snider, B. B.; Li, Z. Total Synthesis and Structure Revision of (±)-Clavilactone D Through Selective Cyclization of an α,β-Dicarbonyl Peroxide. J. Org. Chem. 2017, 82, 5487-5491.
[41] Lv, L.; Lu, S.; Chen, Y.; Li, Z. Diastereoselective Building up Polycyclic Tetrahydrofurans via Tandem Annulation of 1,n-Enynes with Aliphatic Acids. Org. Chem. Front. 2017, 4, 2147-2152.
[42] Lv, L.; Li, Z. Iron-Catalyzed Radical [2+2+2] Annulation of Benzene-Linked 1,7-Enynes with Aldehydes: Fused Pyran Compounds. Org. Lett. 2016, 18, 2264-2267.
[43] Lv, L.; Bai, X.; Yan, X.; Li, Z. Iron-Catalyzed Decarbonylation Initiated [2+2+m] Annulation of Benzene-Linked 1,n-Enynes with Aliphatic Aldehydes. Org. Chem. Front. 2016, 3, 1509-1513.
[44] Lv, L.; Li, Z. Fe-Catalyzed Cross-Dehydrogenative Couplings. Top. Curr. Chem. (Z) 2016, 374, 38. (Invited review)
[45] Lv, L.; Lu, S.; Guo, Q.; Shen, B.; Li, Z. Iron-Catalyzed Acylation-Oxygenation of Terminal Alkenes for the Synthesis of Dihydrofurans Bearing a Quaternary Carbon. J. Org. Chem. 2015, 80, 698-704.
[46] Lv, L.; Xi, H.; Bai, X.; Li, Z. Iron-Catalyzed Convergent Radical Cyclization of Aldehydes with Two Alkenes to 3,4-Dihydropyrans. Org. Lett. 2015, 17, 4324-4327.
[47] Lv, L.; Qi, L.; Guo, Q.; Shen, B.; Li, Z. Iron-Catalyzed Divergent Tandem Radical Annulation of Aldehydes with Olefins toward Indolines and Dihydropyrans. J. Org. Chem. 2015, 80, 12562-12571.
[48] Lv, L.; Shen, B.; Li, Z. Total Synthesis of (+)-Clavilactones A, B, and Proposed D through Iron-Catalyzed Carbonylation–Peroxidation of Olefin. Angew. Chem. Int. Ed. 2014, 53, 4164-4167.
[49] Kan, J.; Chen, Z.; Qiu, Z.; Lv, L.; Li, C.; Li, C.-J. Umpolung Carbonyls Enable Direct Allylation and Olefination of Carbohydrates. Sci. Adv. 2022, 8, eabm6840.
[50] Li, C.-C.; Kan, J.; Qiu, Z.; Li, J.; Lv, L.; Li, C.-J. Synergistic Relay Reactions to Achieve Redox- Neutral a-Alkylation of Olefinic Alcohols with Ruthenium(II)-Catalysis. Angew. Chem. Int. Ed. 2020, 59, 4544-4549.
[51] Yao, J.; Chen, Z.; Yu, L.; Lv, L.; Cao, D.; Li, C.-J. Palladium-Catalyzed Hydroalkylation of Methylenecyclopropanes with Simple Hydrazones. Chem. Sci. 2020, 11, 10759-10763.
[52] Cao, D.; Chen, Z.; Lv, L.; Zeng, H.; Peng, Y.; Li, C.-J. Light-Driven Metal-Free Direct Deoxygenation of Alcohols under Mild Conditions. iScience, 2020, 23, 101419.
[53] Tian, T.; Wang, X.; Lv, L.; Li, Z. Iron-Catalyzed [2+2+2]Annulation of Aliphatic Bridged 1,n- Enynes with Aldehydes for the Synthesis of Fused Pyrans. E. J. Org. Chem. 2020, 4425-4428.
[54] Qiu, Z.; Lv, L.; Li, J.; Li, C.-C.; Li, C.-J. Direct Conversion of Phenols into Primary Anilines with Hvdrazine Catalyzed by Palladium. Chem. Sci. 2019, 10, 4775-4781.
[55] Li, C.-J.; Huang, J.; Dai, X.-J.; Wang, H.; Chen, N.; Wei, W.; Zeng, H.; Tang, J.; Li, C.; Zhu, D.; Lv, L. An Old Dog with New Tricks: Enjoin Wolff-Kishner Reduction for Alcohol Deoxygenation and C-C Bond Formations. Synlett. 2019, 30, 1508-1524.
[56] Zhu, D. ‡ Lv, L. ‡; Qiu, Z.; Li, C.-J. Nickel-Catalyzed Cross-Coupling of Umpolung Carbonyls and Alkyl Halides. J. Org. Chem. 2019, 84, 6312−6322
[57] Tang, J.; Lv, L.; Dai, X.-J.; Li, C.-C.; Li, L.; Li, C.-J. Nickel-Catalyzed Cross-Coupling of Aldehydes with Aryl Halides via Hydrazone Intermediates. Chem. Commun. 2018, 54, 1750-1753.
[58] Li, J. ‡; Zhu, D. ‡; Lv, L.; Li, C.-J. Radical Difluoromethylthiolation of Aromatics Enabled by Visible Light. Chem. Sci. 2018, 9, 5781-5786.
[59] Liu, W. ‡; Liu, P. ‡; Lv, L.; Li, C.-J. Metal-Free and Redox-Neutral Conversion of Organotrifluoroborates into Radicals Enabled by Visible Light. Angew. Chem. Int. Ed. 2018, 57, 13499-13503.
[60] Bai, X.; Lv, L.; Li, Z. Copper-Catalyzed Tandem Trifluoromethylation-Cyclization of Olefinic Carbonyls: Synthesis of Trifluoromethylated 2,3-Dihydrofurans and 3,4-Dihydropyrans. Org. Chem. Front. 2016, 3, 804-808.
[61] Zheng, X.; Lv, L.; Lu, S.; Wang, W.; Li, Z.; Benzannulation of Indoles to Carbazoles and Its Applications for Synthesis of Carbazole Alkaloids. Org. Lett. 2014, 16, 5156-5159.
[62] Lou, C.; Lv, L.*; Li, Z.* Fe-Catalyzed Ring-Opening Reactions of Siloxy Cyclopropanes with Alkenes and TBHP: Synthesis of 4-Ester Peroxides. J. Organomet. Chem. 2022, 977, 122467.
[63] Lou, C.; Lv, L.; Li, Z.* Mn-Catalyzed Ring-Opening Peroxidation of Cyclobutanols: A Method for the Synthesis of 4-Oxo Peroxides. Adv. Synth. Catal. 2022, 364, 3743-3748.
[64] Mao, K.; Ma, Y.; Lv, L.; Li, Z.* [4+1] Cyclization of α-CF3 Carbonyls with Hydrazides: Synthesis of 1,3,4-Oxadiazoles under Ambient Conditions. Asian J. Org. Chem. 2022, 11, e202200334.
[65] Ma, Y.; Mao, K.; Chen, Y.; Lv, L.; Li, Z.* Tandem Defluorination/Annulation of α-CF3 Carbonyls with Bis-Nucleophiles: Stereodivergent Synthesis of 2-Alkylidene-1,3-Heterocycles. Tetrahedron Lett. 2022, 100, 153902.
