中国人民大学
lvleiyang2008@163.com
个人情况：
男，1989.6生，山东省，中共党员
Email：lvleiyang2008@ruc.edu.cn
学习、工作经历：
2020/11—至今， 副教授 中国人民大学 化学系
2017/9—2020/8， 博士后 McGill University/兰州大学 导师 李朝军 院士
2012/9—2017/7, 博士 中国人民大学(本科直博) 导师 李志平 教授
2008/9—2012/7， 学士 青岛科技大学
研究方向：
有机合成与催化
有机氟化学
光催化自由基化学
功能性杂环化合物合成
农药、医药中间体合成
获得奖项：
博士后创新人才支持计划（2017年）
博士生国家奖学金 (2014年，2015年)
光华奖学金 (2016年)
中国人民大学博士生一等奖学金 (5次，2012-2016年)
中国人民大学第十届“学术新星”奖 (2016年)
第十四届全国均相催化“优秀学生报告奖”(2015年)
中国人民大学“科研成果二等奖”（2023年）
主持项目：
国家自然科学基金青年项目
中国人民大学新教师启动项目
学术兼职：
CCL青年编委
参加学术会议：
[1] 中国化学会第十八届全国有机合成学术研讨会议，青年邀请报告，2024年4月17日-4月20日，安徽
[2] 中国化学会第十七届全国氟化学会议，邀请报告，2023年7月8日-7月9日，南京
[3] 中国化学会第33届学术年会，口头报告，2023年6月17日-6月20日，青岛
[4] 中国化学会第十七届全国均相催化学术会议，口头报告，2023年8月14日-17日，西安
[5] 中国化学会第十六届全国氟化学会议，墙报，2021年7月2日-7月5日，天津
[6] 青岛科技大学化学院，学术交流，2023年6月19日，青岛
[7] 中国农业大学理学院，学术交流，2023年11月10日，北京
[8] 南京工业大学化学院，学术交流，2023年7月9日，南京
发表论文：
[1] Qian, H.; Cheng, Z. P.; Luo, Y.; Lv, L.*; Chen, S.*; Li, Z.* Pd/IPrBIDEA-Catalyzed Hydrodefluorination of gem-Difluorocyclopropanes: Regioselective Synthesis of Terminal Fluoroalkenes. J. Am. Chem. Soc. 2024, 146, 24-32.
[2] Feng, Y.; Chen, S.; Lv, L.*; Yaremenko, I. A.*; Terent'ev, A. O.*; Li, Z.* Photocatalytic Sulfonyl Peroxidation of Alkenes via Deamination of N‑Sulfonyl Ketimines. Org. Lett. 2024, 26, 1920-1925.
[3] Yan, Y.; Lu, W.; Qian, H.; Lv, L.*; Li, Z.* Pd-Catalyzed Ring-Opening of gem-Difluorocyclopropanes for the Mono- and Bis-Fluoroallylation of 1,3-Dicarbonyls. Chin. J. Org. Chem. 2024, 44, doi: 10.6023/cjoc202312003.
[4] Lv, L.*; Luo, Y.; Li, Z. Advances in the Synthesis of Organogermaniums Based on the Addition Reactions of Alkenes and Alkynes. Chin. J. Org. Chem. 2024, 44, doi: 10.6023/cjoc202401014.
[5] Lv, L.; Lu, G.; Luo, Y.; Gao, G.; Yan, X.; Xu, Z.; Yao, L.; Li, H.; Li, Z.* Reductive Amination Reaction — Preparation of m-Xylylenediamine from Isophthalaldehyde as an Example: Introduce a Comprehensive Experiment of Organic Chemistry. Univ. Chem. 2024, ASAP.
[6] Qian, H.; Nguyen, H. D.; Lv, L.*; Chen, S.*; Li, Z.* Chemo-, Stereo- and Regioselective Fluoroallylation/Annulation of Hydrazones with gem-Difluorocyclopropanes via Tunable Palladium/NHC Catalysis. Angew. Chem. Int. Ed. 2023, 62, e202303271.
[7] Lou, C.; Feng, Y.; Huang, Q.; Lv, L.*; Li, Z.* Visible Light-Induced Decarboxylative Peroxidation of Carboxylic Acids: Metal-Free Synthesis of Benzyl Peroxides. Asian J. Org. Chem. 2023, 12, e202300408.
[8] Yan, Y.; Qian, H.; Lv, L.*; Li, Z.*. Pd/NHC-Catalyzed Ring-Opening of gem-Difluorocyclopropanes with Malonates Via Selective C-C Bond Cleavage: Synthesis of Monofluoroalkenes. J. Org. Chem. 2024, DOI: 10.1021/acs.joc.3c00744.
[9] Mao, K.; Lv, L.*; Li, Z.* Amine-Induced Selective C–C Bond Cleavage of 2,2,2-Trifluoroethyl Carbonyls for the Synthesis of Ureas and Amides. J. Org. Chem. 2023, 88, 10137–10146.
[10] Lv, L.*; Qian, H. Developments and Applications of Allyl-(aza)allyl Coupling Reactions. Green Synth. Catal. 2023, 4, 190-205.
[11] Luo, Y.; Lv, L.*; Li, Z.* Light-promoted Germylation of Aryl Propiolamides/Alkynoates: Synthesis of Ge-Containing Spiro[4.5]trienones and Vinylgermanes. ChemCatChem 2023, 15, e202300467.
[12] Shu, S.; Wang, L.; Lv, L.*; Li, Z.* Copper-Catalyzed [3+2] Annulation of Pyridinium Ylides with α-CF3 Ketones: Synthesis of Functionalized 2-Fluoroindolizines. Asian J. Org. Chem. 2023, 12, e202300075.
[13] Gao, G.; Lv, L.*; Li, Z.* Three-Component Reactions of 2,2,2-Trifluoroethyl Ketones, Aryl Azides and Aqueous Ammonia for the Synthesis of 4-Cyano-1,2,3-triazoles. Eur. J. Org. Chem. 2023, e202301135.
[14] Lv, L.*; Qian, H.; Crowell, A. B.; Chen, S.*; Li, Z.* Pd/NHC-Controlled Regiodivergent Defluorinative Allylation of gem-Difluorocyclopropanes with Allylboronates. ACS Catal. 2022, 12, 6495-6505.
[15] Lv, L.*; Qian, H.; Li, Z.* Catalytic Diversification of gem-Difluorocyclopropanes: Recent Advances and Challenges. ChemCatChem 2022, 14, e202200890.
[16] Liu, F.; Lv, L.*; Ma, Y.*; Li, Z.* Copper-Catalyzed Radical Difluoromethylation-Peroxidation of Alkenes: Synthesis of β-Difluoromethyl. Peroxides. Asian J. Org. Chem. 2022, 11, e202200393.
[17] Wang, L.; Shu, S.; Lv, L.*; Li, Z.* Copper-Catalyzed Remote Trifluoromethylthiolation-Peroxidation of Unactivated Alkenes via 1,5-Hydrogen Atom Transfer. Tetrahedron Lett. 2022, 104, 154029.
[18] Gao, G.; Mao, K.; Lv, L.*; Li, Z.* Three-Component Coupling of α-Trifluoromethyl Carbonyls, Azides and Amines for the Regioselective Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles. Adv. Synth. Catal. 2022, 364, 1402-1408.
[19] Luo, Y.; Xu, B.; Lv, L.*; Li, Z.* Copper-Catalyzed Three-Component Germyl Peroxidation of Alkenes. Org. Lett. 2022, 24, 2425-2430.
[20] Luo, Y.; Lv, L.*; Li, Z.* Copper-Catalyzed Germyl-Azidation of Alkenes with Germanium Hydrides and Trimethylsilyl Azide. Org. Lett. 2022, 24, 8052-8056.
[21] Ma, Y.; Lv, L.*; Li, Z.* β-Perfluoroalkyl Peroxides as Fluorinated C3-Building Blocks for the Construction of Benzo[4,5]imidazo[1,2-a]pyridines. J. Org. Chem. 2022, 87, 1564-1573.
[22] Wang, L.; Lv, L.*; Li, Z.* Concomitant Functionalization of Two Different Ketones by Merging Brønsted Acid Catalysis and Radical Relay Coupling. Org. Chem. Front. 2022, 9, 1561-1566.
[23] Lv, L.*; Qian, H.; Ma, Y.; Huang, S.; Yan, X.; Li, Z.* Ligand-Controlled Regioselective and Chemodivergent Defluorinative Functionalization of gem-Difluorocyclopropanes with Simple Ketones. Chem. Sci. 2021, 12, 15511-15518. (Hot paper)
[24] Lv, L.; Gao, G.; Luo, Y.; Mao, K.; Li, Z.* Three-Component Reactions of Alpha-CF3 Carbonyls, NaN3, and Amines for the Synthesis of NH-1,2,3-Triazoles. J. Org. Chem. 2021, 86, 17197-17212.
[25] Lou, C.; Wang, X.; Lv, L.*; Li, Z.* Iron-Catalyzed Ring-Opening Reactions of Cyclopropanols with Alkenes and TBHP: Synthesis of 5-Oxo Peroxides. Org. Lett. 2021, 23, 7608-7612.
[26] Luo, Y.; Tian, T.; Nishihara, Y.; Lv, L.*; Li, Z.* Iron-Catalysed Radical Cyclization to Synthesize Germanium-Substituted Indolo[2,1-a]isoquinolin-6(5H)-ones and Indolin-2-ones. Chem. Commun. 2021, 57, 9276-9279.
[27] Wang, X.; Lou, C.; Lv, L.*; Li, Z.* Annulative pi-Extension (APEX) of Indoles to Pyrido[1,2-a]indoles Using 4-Oxo Peroxides as C4 Units. Org. Lett. 2021, 23, 5978-5982.
[28] Ma, Y.; Chen, Y.; Lv, L.*; Li, Z.* Regioselective Synthesis of Emission Color‐Tunable Pyrazolo[1,5‐a]pyrimidines with β,β‐Difluoro Peroxides as 1,3‐Bis‐Electrophiles. Adv. Synth. Catal. 2021, 363, 3233-3239.
[29] Wang, L.; Ma, Y.; Jiang, Y.; Lv, L.*; Li, Z.* A Mn-Catalyzed Remote C(sp3)-H Bond Peroxidation Triggered by Radical Trifluoromethylation of Unactivated Alkenes. Chem. Commun. 2021, 57, 7846-7849.
[30] Lv, L.*; Li, C.-J.* Pd-Catalyzed Defluorinative Alkylation of gem-Difluorocyclopropanes: Switching Regioselectivity via Simple Hydrazones. Angew. Chem. Int. Ed. 2021, 60, 13098-13104.
[31] Li, L.; Huang, S.; Mao, K.; Lv, L.*; Li, Z.* Synthesis of Isoxazoles via Cyclization of β-Fluoro Enones with Sodium Azide. Tetrahedron Lett. 2021, 71, 153052.
[32] Lv, L.*; Li, C.-J.* Ruthenium Catalyzed β-Selective Alkylation of Vinylpyridines with Aldehydes/Ketones via N2H4 Mediated Deoxygenative Couplings. Chem. Sci. 2021, 12, 2870-2875.
[33] Tian, T.; Wang, X.; Lv, L.*; Li, Z.* Iron-Catalyzed Acylation-Functionalization of Unactivated Alkenes with Aldehydes. Chem. Commun. 2020, 56, 14637-14640.
[34] Yu, L. ‡; Lv, L. ‡; Qiu, Z.; Chen, Z.; Tan, Z.; Liang, Y.-F.; Li, C.-J.* Pd-Catalyzed Formal Hydroalkylation of Aryl-Substituted Alkynes with Hydrazones. Angew. Chem. Int. Ed. 2020, 59, 14009-14013. (contributed equally) (Hot paper)
[35] Lv, L. ‡; Yu, L. ‡; Qiu, Z.; Li, C.-J.* Switch in Selectivity for the Formal Hydroalkylation of 1,3-Dienes and Enynes with Simple Hydrazones. Angew. Chem. Int. Ed. 2020, 59, 6466-6472. (VIP paper)
[36] Lv, L. ‡; Zhu, D. ‡; Li, C.-J.* Direct Dehydrogenative Alkyl Heck-Couplings of Vinylarenes with Umpolung Aldehydes Catalyzed by Nickel. Nat. Commun. 2019, 10, 715.
[37] Lv, L. ‡; Qiu, Z. ‡; Li, J.; Liu, M.; Li, C.-J.* N2H4 as Traceless Mediator for Homo- and Cross- Aryl Coupling. Nat. Commun. 2018, 9, 4739.[38] Lv, L. ‡; Zhu, D. ‡; Tang, J.; Qiu, Z.; Li, C.-C.; Gao, J.; Li, C.-J.* Cross-Coupling of Phenol Derivatives with Umpolung Aldehydes Catalyzed by Nickel. ACS Catal. 2018, 8, 4622-4627.
[39] Lv, L.; Zhu, D.; Qiu, Z.; Li, J.; Li, C.-J.* Nickel-Catalyzed Regioselective Hydrobenzylation of 1,3-Dienes with Hydrazones. ACS Catal. 2019, 9, 9199-9205.
[40] Zhu, D.‡; Lv, L.‡; Li, C.-C.; Ung, S.; Gao, J.; Li, C.-J.* Umpolung of Carbonyls as Alkyl Organometallic Reagent Surrogates for Palladium Catalyzed Allylic Alkylation. Angew. Chem. Int. Ed. 2018, 57, 16520-16524. (contributed equally)
[41] Zhou, Z.-Z.‡; Liu, M.‡; Lv, L.‡; Li, C.-J.* Silver (I)-Catalyzed Widely Applicable Aerobic 1,2-Diol Oxidative Cleavage. Angew. Chem. Int. Ed. 2018, 57, 2616-2620. (contributed equally)
[42] Lv, L.*; Li, Z.* FeCl3-Catalyzed Regio-Divergent Carbosulfenylation of Unactivated Alkenes: Construction of Medium-Sized Ring. J. Org. Chem. 2018, 83, 10985-10994.
[43] Lv, L.; Li, Z.* Iron-Catalyzed Oxidative Cyclization of 1,6-Enones with Aldehydes: Synthesis of Functionalized 3,4-Dihydro-2H-pyrans. Chin. J. Chem. 2017, 35, 303-306.
[44] Lv, L.; Li, Z.* Cycloalkylation of C(sp3)-H Bond with Neighboring Carboxylic Acid as Traceless Activating Group. J. Org. Chem. 2017, 82, 2689-2702.
[45] Lv, L.; Snider, B. B.; Li, Z.* Total Synthesis and Structure Revision of (±)-Clavilactone D Through Selective Cyclization of an α,β-Dicarbonyl Peroxide. J. Org. Chem. 2017, 82, 5487-5491.
[46] Lv, L.; Lu, S.; Chen, Y.; Li, Z.* Diastereoselective Building up Polycyclic Tetrahydrofurans via Tandem Annulation of 1,n-Enynes with Aliphatic Acids. Org. Chem. Front. 2017, 4, 2147-2152.
[47] Lv, L.; Li, Z.* Iron-Catalyzed Radical [2+2+2] Annulation of Benzene-Linked 1,7-Enynes with Aldehydes: Fused Pyran Compounds. Org. Lett. 2016, 18, 2264-2267.
[48] Lv, L.; Bai, X.; Yan, X.; Li, Z.* Iron-Catalyzed Decarbonylation Initiated [2+2+m] Annulation of Benzene-Linked 1,n-Enynes with Aliphatic Aldehydes. Org. Chem. Front. 2016, 3, 1509-1513.
[49] Lv, L.; Li, Z.* Fe-Catalyzed Cross-Dehydrogenative Couplings. Top. Curr. Chem. (Z) 2016, 374, 38. (Invited review)
[50] Lv, L.; Lu, S.; Guo, Q.; Shen, B.; Li, Z.* Iron-Catalyzed Acylation-Oxygenation of Terminal Alkenes for the Synthesis of Dihydrofurans Bearing a Quaternary Carbon. J. Org. Chem. 2015, 80, 698-704.
[51] Lv, L.; Xi, H.; Bai, X.; Li, Z.* Iron-Catalyzed Convergent Radical Cyclization of Aldehydes with Two Alkenes to 3,4-Dihydropyrans. Org. Lett. 2015, 17, 4324-4327.
[52] Lv, L.; Qi, L.; Guo, Q.; Shen, B.; Li, Z.* Iron-Catalyzed Divergent Tandem Radical Annulation of Aldehydes with Olefins toward Indolines and Dihydropyrans. J. Org. Chem. 2015, 80, 12562-12571.
[53] Lv, L.; Shen, B.; Li, Z.* Total Synthesis of (+)-Clavilactones A, B, and Proposed D through Iron-Catalyzed Carbonylation–Peroxidation of Olefin. Angew. Chem. Int. Ed. 2014, 53, 4164-4167.
[54] Zhu, D. ‡ Lv, L. ‡; Qiu, Z.; Li, C.-J.* Nickel-Catalyzed Cross-Coupling of Umpolung Carbonyls and Alkyl Halides. J. Org. Chem. 2019, 84, 6312−6322. (contributed equally)
[55] Kan, J.; Chen, Z.; Qiu, Z.; Lv, L.; Li, C.; Li, C.-J.* Umpolung Carbonyls Enable Direct Allylation and Olefination of Carbohydrates. Sci. Adv. 2022, 8, eabm6840.
[56] Li, C.-C.; Kan, J.; Qiu, Z.; Li, J.; Lv, L.; Li, C.-J.* Synergistic Relay Reactions to Achieve Redox- Neutral a-Alkylation of Olefinic Alcohols with Ruthenium(II)-Catalysis. Angew. Chem. Int. Ed. 2020, 59, 4544-4549.
[57] Yao, J.; Chen, Z.; Yu, L.; Lv, L.; Cao, D.; Li, C.-J.* Palladium-Catalyzed Hydroalkylation of Methylenecyclopropanes with Simple Hydrazones. Chem. Sci. 2020, 11, 10759-10763.
[58] Cao, D.; Chen, Z.; Lv, L.; Zeng, H.; Peng, Y.; Li, C.-J.* Light-Driven Metal-Free Direct Deoxygenation of Alcohols under Mild Conditions. iScience, 2020, 23, 101419.
[59] Tian, T.; Wang, X.; Lv, L.; Li, Z.* Iron-Catalyzed [2+2+2] Annulation of Aliphatic Bridged 1,n-Enynes with Aldehydes for the Synthesis of Fused Pyrans. E. J. Org. Chem. 2020, 4425-4428.
[60] Qiu, Z.; Lv, L.; Li, J.; Li, C.-C.; Li, C.-J.* Direct Conversion of Phenols into Primary Anilines with Hydrazine Catalyzed by Palladium. Chem. Sci. 2019, 10, 4775-4781.
[61] Li, C.-J.*; Huang, J.; Dai, X.-J.; Wang, H.; Chen, N.; Wei, W.; Zeng, H.; Tang, J.; Li, C.; Zhu, D.; Lv, L. An Old Dog with New Tricks: Enjoin Wolff-Kishner Reduction for Alcohol Deoxygenation and C-C Bond Formations. Synlett. 2019, 30, 1508-1524.
[62] Tang, J.; Lv, L.; Dai, X.-J.; Li, C.-C.; Li, L.; Li, C.-J.* Nickel-Catalyzed Cross-Coupling of Aldehydes with Aryl Halides via Hydrazone Intermediates. Chem. Commun. 2018, 54, 1750-1753.
[63] Li, J. ‡; Zhu, D. ‡; Lv, L.; Li, C.-J.* Radical Difluoromethylthiolation of Aromatics Enabled by Visible Light. Chem. Sci. 2018, 9, 5781-5786.
[64] Liu, W. ‡; Liu, P. ‡; Lv, L.; Li, C.-J.* Metal-Free and Redox-Neutral Conversion of Organotrifluoroborates into Radicals Enabled by Visible Light. Angew. Chem. Int. Ed. 2018, 57, 13499-13503.
[65] Bai, X.; Lv, L.; Li, Z.* Copper-Catalyzed Tandem Trifluoromethylation-Cyclization of Olefinic Carbonyls: Synthesis of Trifluoromethylated 2,3-Dihydrofurans and 3,4-Dihydropyrans. Org. Chem. Front. 2016, 3, 804-808.
[66] Zheng, X.; Lv, L.; Lu, S.; Wang, W.; Li, Z.* Benzannulation of Indoles to Carbazoles and Its Applications for Synthesis of Carbazole Alkaloids. Org. Lett. 2014, 16, 5156-5159.
[67] Lou, C.; Lv, L.*; Li, Z.* Fe-Catalyzed Ring-Opening Reactions of Siloxy Cyclopropanes with Alkenes and TBHP: Synthesis of 4-Ester Peroxides. J. Organomet. Chem. 2022, 977, 122467.
[68] Lou, C.; Lv, L.; Li, Z.* Mn-Catalyzed Ring-Opening Peroxidation of Cyclobutanols: A Method for the Synthesis of 4-Oxo Peroxides. Adv. Synth. Catal. 2022, 364, 3743-3748.
[69] Mao, K.; Ma, Y.; Lv, L.; Li, Z.* [4+1] Cyclization of α-CF3 Carbonyls with Hydrazides: Synthesis of 1,3,4-Oxadiazoles under Ambient Conditions. Asian J. Org. Chem. 2022, 11, e202200334.
[70] Ma, Y.; Mao, K.; Chen, Y.; Lv, L.; Li, Z.* Tandem Defluorination/Annulation of α-CF3 Carbonyls with Bis-Nucleophiles: Stereodivergent Synthesis of 2-Alkylidene-1,3-Heterocycles. Tetrahedron Lett. 2022, 100, 153902.
